Wayne Wilderson

An outbreak of a sexually transmitted disease affects several members of the hospital staff, prompting Chief Webber to call a meeting. Meanwhile, the chief reluctantly confides to Dr. (Derek) Shepherd about his own medical concerns; Izzie and Cristina are worried by a patient's wife and daughter who are at odds over his care; Burke treats Bill, a college buddy whose medical diagnosis raises some questions regarding his wife's actions; and, just as Meredith and Derek grow more intimate, a bombshell is dropped.

After Alan and Charlie tell Evelyn that none of her acquaintances will mourn her when she dies, she bitterly ignores them for a few weeks. The guys then discover that, instead of trying to be more pleasant to the people she knows, Evelyn has brought together a whole new group of "friends," including two men and a cute boy who seem suspiciously like adoring versions of Charlie, Alan and Jake. Meanwhile, Jake develops an interesting new way of speaking.

Roz has heard a juicy piece of gossip that one of the highly paid stars on KACL has to be fired and tells Frasier. When Frasier tells the rumour to Father Mike, an interesting chain of events ensues.

Old friends Jim and Pam are back together after months apart as the Scranton branch and Stamford branch are finally merged.

Michael tries to be supportive when he finds out one of his new employees, presumably someone from the Stamford branch, has a prison record.