Better known as the Asperger's Are Us troupe, Noah, Ethan, Jack and New Michael kick off their US tour in Boston.

In New York City, the troupe prepare to play at legendary comedy venue Caroline's. When the show proves harder than expected and some jokes aren't well received, the guys begin to question whether it was all worth it.

In North Carolina, Noah, Ethan, Jack and New Michael are met with unexpected feedback from the audience. Then, everyone is annoyed when New Michael starts drinking during a show in Tennessee.

In Cincinnati, the troupe do a show that quickly spirals out of control. Then they move on to Dayton, Noah's hometown, where they hope to get the tour back on track.

In the final week of the tour, Ethan starts to question himself and the purpose for the whole tour. Then, the troupe race to get to Seattle in time for their show, as they face their worst RV problems yet.

Noah, Ethan, Jack and New Michael prepare their last show in Los Angeles, as their six week tour comes to an end. At the end of it all, they look back on their experiences, as they bid farewell to the troublesome RV and their life on the road.