Humanity embarks upon a secret project that could save Earth from alien aggressors; while on a critical mission to Mars, Susumu Kodai receives sad news.

On the red earth lies an interstellar spaceship that was secretly constructed by humans. It has a mission: The crew is to take a trip to the planet Iscandar, which is 168,000 light years away.

When the Yamato stops at a mysterious land mass orbiting Jupiter to make repairs, the crew makes a surprising discovery.

Susumu leads a search party on one of Saturn's moons to answer a distress call and fall into a trap.

The Yamato targets a Gamilan base on Pluto but triggers a nasty surprise.

The Yamato fools the Gamilans into believing the ship was destroyed, giving the crew the chance to locate and attack the main base on Pluto.