Mickey, who is intelligent but lacking ambition, is always hustling and looking for the next easy payday. It seems like her ship has finally come in when she goes to Connecticut to visit her estranged sister and billionaire brother-in-law in search of a handout, and they flee the country to avoid federal fraud charges, leaving her with everything. But nothing in life is free, and `everything' includes guardianship of her sister's three ill-mannered children - teenage Sabrina, future Republican and middle child Chip, and the fragile youngest, Ben. Though motherhood was never in her plans, Mickey discovers a little responsibility never hurt anybody.