Pemeran & Kru
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Robert DowneySherlock Holmes - Jude LawDr. John Watson
- Noomi RapaceMadam Simza Heron
- Jared HarrisProfessor James Moriarty
- Rachel McAdamsIrene Adler
- Stephen FryMycroft Holmes
- Eddie MarsanInspector Lestrade
- Kelly ReillyMary Watson
- Jack LaskeyCarruthers
- Geraldine JamesMrs. Hudson
- William HoustonConstable Clark
- Paul AndersonColonel Sebastian Moran
- Wolf KahlerDoctor Hoffmanstahl
- Iain MitchellAuctioneer
- Guy RitchieSutradara
- Joel SilverProduser
- Lionel WigramProduser
- Susan DowneyProduser
- Dan LinProduser
- Bruce BermanProduser
- Steve Clark-HallProduser
- Michele MulroneyPenulis
- Kieran MulroneyPenulis
- Tony PeckhamPenulis