In hopes of reconnecting with his estranged child, a father (Golden Globe-Winner Ewan McGregor) embarks on an impromptu road trip with his now-adult daughter (Clara McGregor) after she has a near-fatal drug overdose. He is planning to take her to rehab - though she doesn't know that. En route to their destination of Santa Fe, New Mexico, and encountering an eccentric array of characters along the way, the two are forced to confront the issues of their past, the trip proving less about the road that they're on, and more about the troubled one from their past.