Alex (Owen Campbell) leaves his girlfriend Lucy (Chloë Levine) after an emotional night, walking the streets alone to get home. From out of nowhere, he is stabbed in a frenzied attack, the life draining out of him. He awakes to find he is the brain in a body he does not recognize. This creature, Adam (Alex Breaux), has been brought into consciousness by Henry (David Call), a brilliant field surgeon suffering from PTSD after two tours in the Mideast, and his accomplice Polidori (Joshua Leonard), a predator determined to cash in on the experiment that brought Adam to life. Henry is increasingly consumed with remorse over what he’s done. Only Liz (Ana Kayne), Henry’s estranged girlfriend, reaches out to consider the creature’s loneliness. But that can’t save him: when Adam finally discovers a video documenting his own origin, he goes on a rampage that reverberates through the group and tragedy befalls them all.