With Lincoln's execution now just a day away, Michael looks for a way to get him out of solitary confinement in time for an escape. Meanwhile, Veronica comes out of hiding and gains an ally.
Flashbacks shed light on the past actions that led to the incarceration of Lincoln, Sucre, T-Bag and C-Note. Also, the basis of Michael's ingenious break-out plan is revealed, and Sara recalls how she ended up working at Fox River.
Lincoln worries about Michael's sanity while Michael is having trouble remembering some parts of the prison schematics, and Sucre has to conceal the hole in the guard's break room.
Michael and a badly wounded Lincoln try to outmanoeuvre Mahone, who is hot on their trail, and enlist the help of an old friend. Meanwhile, Sara is arrested upon her release from hospital.
Michael, Lincoln, Sucre and Aldo Burrows make a run for the getaway plane, but Mahone has other ideas. Meanwhile, Sara fights back and manages to escape from Kellerman, and Bellick becomes a suspect in the murder of Roy Geary.