Greg Pitts

The O'Malley Family visits George at the hospital, Meredith is determined to have a more positive outlook on life, Derek and Addison strive for a civil relationship, and Richard endeavors to reunite with his wife, Adele.

The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner at Meredith's -- but it remains to be seen who among the invited guests will actually show up. Meanwhile, George endures the O'Malley tradition of hunting turkeys with his less-than-sophisticated family, and Meredith treats a patient who's been in a vegetative state for 16 years.

After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part One of a two-part episode.

After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part Two of a two-part episode.

Recent events strain Burke and Cristina's relationship, Meredith's half-sister, Molly, is admitted to the hospital, and Mark and Derek must work together when two close-knit brothers seek medical help.

Mike feels let down when his daughters aren't into celebrating Halloween with him the way they used to.