A recent attendee at a popular motivational speaker's conference in Seattle is murdered. The BAU looks at the speaker as the main suspect, but they have to refocus their investigation when the speaker himself goes missing.
The team grow increasingly concerned about their mentor and suspect he may have developed a new drug problem. House revives a boxer's flagging career as well.
The team is involved in an international incident as they investigate the murder of an American petty officer whose body was found aboard a British ship.
Jack and Cole team up to protect New York City from the catastrophic threat. Meanwhile, CTU is further buckled by a hostage situation and Prady's presence.