House suffers head trauma and short-term memory loss after being involved in a bus crash. While his colleagues urge him to rest, House is plagued by the belief that he noticed someone with a life-threatening illness on the bus, but cannot remember who they were.
Dr Rhodes persuades Dr Latham to accompany him on a medical trip out of town. Meanwhile, an 8-year-old cancer patient wants to give up his battle.
A gang member is arrested for murder, and Jax must choose between friendship and loyalty to the club.
A white-separatist group moves into Charming to challenge SAMCRO, Clay strikes a new gun deal with the IRA, Bobby is released from jail, and Opie returns seeking revenge for Donna's murder.
Clay's solution to getting cash for Bobby's defence leaves SAMCRO in a vulnerable position; Abel's happy homecoming ends in turmoil for the club.