The BAU is called to Oklahoma City to help local authorities track a serial killer who removes the eyes of his murder victims.
Lois and Hal leave the boys with Francis for the weekend, promising that, if all goes well, Francis may not have to go back to military school. However, mayhem ensues and Malcolm requires hospitalisation.
When the family takes a vacation to a casino, Hal is banned from gambling and takes Malcolm and Reese on an ill-fated trek into the desert. Meanwhile, Lois and Dewey win a free day of spa pampering and Francis spends a lonely weekend at home.
Malcolm tries to help Reese bring his grades up, while Francis is exiled to a friend's house after defying Lois's order to patch the roof.
Reese is accused of stealing at his new job, Dewey tries to convince his parents he can keep a goldfish alive, and Malcolm chafes when a super-genius joins his class.