Agents investigate a DJ smuggling ecstasy in cans of dog food. Agents are hot on the trail of weapons smugglers. A luxury boat with a checkered history catches agents' attention. Agents locate a boat with people smugglers attempting to make landfall.

HSI agents coordinate a massive raid to take down a transnational drug trafficking gang. Agents interdict an erratically moving vessel, often a sign of evasive smugglers, but it turns out that its passengers have less sinister motives.

Officers race to Port Newark, where a West African car gang is getting ready to ship a stolen luxury vehicle out of the country. Using the owner's GPS tracker on the car, they attempt to identify the container it's in before the ship leaves port.

Agents investigate a small boat crewed by three men on a well-known smuggling route, only to confirm the men have a shady past. An agent finds lifejackets and clothing abandoned on the beach, evidence of a recent illegal migrant landing.

Agents must abort a mission when an incoming tropical storm rolls in. A cruise ship passenger baulks at paying US duty on cigarettes. Illicit packages dumped at sea begin washing up on Florida's beaches. A Brazilian vessel intrigues agents.

Agents conducting a random stop-search inspection of vehicles coming off a car ferry get a hit. Officers come across a shipment of 80,000 t-shirts that may all be counterfeit. Agents descend into a mangrove forest to rescue stranded migrants.