କାଷ୍ଟ୍ ଓ କ୍ରୂ
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ରବର୍ଟ ଡାଓନି ଜୁନିୟରSherlock Holmes - Jude LawDr. John Watson
- Noomi RapaceMadam Simza Heron
- Jared HarrisProfessor James Moriarty
- Rachel McAdamsIrene Adler
- Stephen FryMycroft Holmes
- Eddie MarsanInspector Lestrade
- Kelly ReillyMary Watson
- Jack LaskeyCarruthers
- Geraldine JamesMrs. Hudson
- William HoustonConstable Clark
- Paul AndersonColonel Sebastian Moran
- Wolf KahlerDoctor Hoffmanstahl
- Iain MitchellAuctioneer
- Guy Ritchieନିର୍ଦ୍ଦେଶକ
- Joel Silverପ୍ରଯୋଜକ
- Lionel Wigramପ୍ରଯୋଜକ
- Susan Downeyପ୍ରଯୋଜକ
- Dan Linପ୍ରଯୋଜକ
- Bruce Bermanପ୍ରଯୋଜକ
- Steve Clark-Hallପ୍ରଯୋଜକ
- Michele Mulroneyଲେଖକ
- Kieran Mulroneyଲେଖକ
- Tony Peckhamଲେଖକ