The T-virus unleashed by the evil Umbrella Corporation has spread to every corner of the globe, infesting the planet with zombies, demons and monsters. Alice, a former Umbrella employee turned rogue warrior, joins her friends on a last-chance mission to storm the company's headquarters located deep underneath what used to be Raccoon City. But the Red Queen knows that Alice is coming, and the final battle will determine if the rest of mankind lives or dies.