A Philadelphia police officer believes a string of suspected overdoses among sex workers in her district may be homicides, and she may have a personal connection; when a red truck seems to be following her, she fears for her family's safety.

Mickey grapples with guilt about her sister as questions mount surrounding the murdered women; Truman connects Mickey to a new suspect in the case; Mickey takes drastic measures to keep Thomas at his private school.

Mickey puts herself in danger while following up on the Dock lead; Mickey brings Thomas and Truman to her family's Thanksgiving; Paula's reaction to a new piece of evidence makes Mickey question everything.

Thomas' birthday party stirs up painful childhood memories for Mickey as tensions with Simon boil over; an unexpected connection between the murder victims leads Mickey and Truman to pursue a new lead.

Mickey and Truman grow closer as they follow their new lead; a new victim complicates the case of the murdered women and raises the stakes in the hunt to find Kacey; Mickey reckons with her past choices.

An unlikely ambush leaves Mickey reeling; Mickey and Truman's bond deepens as they spend the holidays together with Thomas; a Christmas revelation helps Mickey get closer to the truth about Kacey, but it drives a wedge between her and Gee.