A woman with backwards hands and feet; a young girl gets a new face; an enormous mystery tumor.

A woman's arm burns from the inside out; a girl undergoes life-changing surgery to stop her neck from dislocating; a boy has a large tumor removed from his face.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark.

Rebecca vomits up to 12 times an hour and is regularly hospitalized; Jacque has a lymphatic malformation in her face that means she has never talked.

Daria was born with a genetic disorder that's left her with a deformed mouth and jaw; Isaiah was born with his organs back to front and no jaw at all.