When things from Billie's past begin to come to light, the team struggles to find the best way to support her; with the nurse shortage in full swing, a simple cleaning job turns into a horrific disaster.
An old friend's heart problems reveal a bigger issue than anticipated; Devon treats a suicidal woman whom he thinks might be a good candidate for deep brain stimulation; Billie and Trevor have an emotional reunion.
Devon treats his first patient with a revolutionary medical fluid that doesn't go as planned; an overdosed John Doe is rushed to Chastain, leading Conrad straight into a much bigger scandal than he expected.
With Raptor on leave to take care of his mother, the hospital scrambles to stay organised without him; a camping trip leaves a patient with a fatal disease that none of the doctors have seen before; Bell and Kit devise a plan to help their case.