Recent events strain Burke and Cristina's relationship, Meredith's half-sister, Molly, is admitted to the hospital, and Mark and Derek must work together when two close-knit brothers seek medical help.
A traumatic car accident fills the ER, Cristina has a crisis of conscience about her deceptive teamwork with Burke, and Izzie pushes the boundaries of her probation.
The O'Malley Family visits George at the hospital, Meredith is determined to have a more positive outlook on life, Derek and Addison strive for a civil relationship, and Richard endeavors to reunite with his wife, Adele.
After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part One of a two-part episode.
After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part Two of a two-part episode.