Setsuko Karasuma is an actress and model born in Ōtsu, Shiga Prefecture, Japan. She attended Chukyo University, but left before finishing. She is employed by the From First Production talent agency. Karasuma made her debut as a Clarion Girl in 1980, moving quickly into the gravure idol scene. Her debut as a film actress came as she got the lead role in the 1980 adaptation of the Hiroyuki Itsuki novel Four Seasons・Natsuko.