Shiki Tohno sustains a life threatening injury as a child and is unable to remember things well before the accident. Due to the accident he was sent away to live with another relative. His sister has him move back in with the family once their Father dies. The day he moves back home he decapitates a woman with the stab of his knife in a moment of insanity. The woman suddenly shows back up alive and asks him to be her boyguard. Shiki accepts and begins to find out what happened in his past.

Arcueid is on a mission to kill a serial vampire that is on a killing spree. Arc and Nero have to run away.

Shiki wakes up in Arcueid's room and discovers one of his friends is missing. Arcueid thinks Shiki has they eyes of death and is able to see death things. They also try to lure Nero and have have Shiki kill him.

Tohno goes back home but has a hard time explaining to Akiha where he has been. All his friends think he has a girlfriend.

Arc becomes upset because Tohno suspects her for some of the killings.

All the boys of 2-B are missing and have been turned into shishas. Tohno tells his friends that he will go to the amusement park with them this weekend. Arc starts working as a model.