Olivia Khoshatefeh

The recipient of Max's sister's heart arrives at New Amsterdam just as Max convinces Sharpe to take a risk on his course of treatment; Frome works to help a trans patient; Bloom grapples with a difficult conversation.

When an inmate comes in with an entirely preventable illness, Max, Sharpe and Iggy head directly to the source -- Rikers Island; Bloom struggles with her recovery; Reynolds gets news that could change his life.

When women who are on a retreat end up in the ED, Max gets some troubling information that could put a patient in jeopardy; Sharpe and Kapoor work together to mend fences between two feuding sisters.

New Amsterdam is still reeling from the pandemic as a plane crash lands in the East River; when investigators come to interrogate the flight crew, Iggy fights against the clock to help the pilot uncover the truth; Max tracks down scarce medication.

Sharpe offers help to a reluctant Mina; Max is faced with a tough decision about Luna; Bloom and Casey treat a patient hiding a lifelong secret; Iggy finds himself in a very dangerous predicament; Reynolds treats a young heart transplant patient.

When an elder care facility shuts down, New Amsterdam is forced to take in many new patients; Max struggles with his decision to head back to London; Reynolds takes his personal frustrations out on his department with near disastrous results.