After his wife was murdered, decorated soldier of fortune MacGruber turned his back on a life of violence, but when her killer, arms dealer Dieter Von Cunth, steals a nuclear warhead, the all-American hero leaps back into action. MacGruber assembles a crack team, including young police lieutenant Dixon Piper and old friend Vicki St Elmo, and with their help battles to stop his arch-nemesis destroying Washington DC.