Derek and the attendings go out to celebrate when he gets the grant he needs for his clinical trial; Meredith and Alex must fend for themselves during the night shift.
The Behavioural Analysis Unit is called in on a Denver case where a home invasion led to the slaughter of an entire family.
Martin is wracked with guilt when he fails to prevent Mike, a 12-year-old boy, from being dragged into a car outside of the boy's school.
Melinda comes across a young girl who shares the same ability as her and later discovers that Gabriel has been trying to lead other ghost whisperers to Grandview.