When a young surgeon with autism and savant syndrome joins St. Bonaventure hospital's surgical unit, he must navigate the new environment and relationships in order to prove that his medical gifts will save lives.

As St Bonaventure's newest surgical resident, Shaun's blunt and awkward bedside manner has landed him in his boss's crosshairs.

Dr Melendez and Dr Unger discover their patient isn't being completely honest with them. Dr Browne must learn to communicate with Dr Murphy as they race back to the hospital with a donated organ.

Shaun makes a huge step forward with his colleagues, as the team wade into murky legal waters regarding a new patient.

Dr Shaun Murphy encounters a young patient who looks eerily similar to his deceased brother. Shaun discovers his parents hid his diagnosis from him, and the team must find the cause of their patients' increasingly severe allergic reactions.

Shaun and Claire devise an experimental procedure to save the leg and life of a young groom. Jared struggles to emotionally connect with a patient whose scars may prove too deep to overcome.