When Manny and Luke baby-sit Lily so the adults can have a day to themselves, things go awry and Claire is convinced the boys are throwing a party.
Meredith learns Amelia's true feelings about Seattle; Bailey deals with the consequences of her actions; Callie receives terrible news; news of a firing causes panic among the residents.
Cristina considers her future at the hospital; Amelia and Derek collaborate on a tough surgery involving conjoined twins; Jo takes on too many cases at once; Stephanie stumbles on the truth about Bailey's case.
Cristina won't let herself get excited when she is nominated for a Harper Avery award; Alex thinks about making a change; Callie and Derek work with a machine that recognizes emotions.
Meredith helps Cristina draft an acceptance speech; Derek feels the weight of his responsibilities; April and Jackson are at odds about children and religion; Callie and Arizona try to reconnect.