Cast & Crew
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Tobey MaguirePeter Parker / Spider-Man - Kirsten DunstMary Jane Watson
- James FrancoHarry Osborn
- Alfred MolinaDoc Ock / Dr. Otto Octavius
- Rosemary HarrisMay Parker
- J.K. SimmonsJ. Jonah Jameson
- Donna MurphyRosalie Octavius
- Daniel GilliesJohn Jameson
- Dylan BakerDr. Curt Connors
- Bill NunnJoseph "Robbie" Robertson
- Vanessa FerlitoLouise
- Joey DiazTrain Passenger
- Aasif MandviMr. Aziz
- Willem DafoeGreen Goblin / Norman Osborn
- Cliff RobertsonBen Parker
- Ted RaimiHoffman
- Elizabeth BanksMiss Brant
- Bruce CampbellSnooty Usher
- Gregg EdelmanEdelman
- Elya BaskinMr. Ditkovich
- Michael Edward ThomasMan at Fire
- Peter McRobbieOsCorp Representative
- John LandisDoctor
- Daniel Dae KimRaymond
- Parry ShenVoice Artist
- Sam RaimiDirector
- Avi AradProducer
- Joseph M. CaraccioloProducer
- Laura ZiskinProducer
- Kevin FeigeProducer
- Stan LeeProducer
- Alvin SargentWriter
- Alfred GoughWriter
- Miles MillarWriter
- Michael ChabonWriter