Meredith learns Amelia's true feelings about Seattle; Bailey deals with the consequences of her actions; Callie receives terrible news; news of a firing causes panic among the residents.
A skull smashes the windshield of a car driven by a group of teenagers on the freeway; a trail of suspects leads Brennan and Booth to a strange cannibalistic society; Cam suggests that Angela hire a private investigator to find her ex-husband.
The BAU team investigates the mass murder of college students, similar to wartime methods used by an Indian tribe long ago.
Kitty finds herself torn between two men; Justin's new job is more than he bargained for; Sarah and Joe face their greatest challenge yet as parents.
The Cigarette-Smoking Man offers to show Scully the cure for cancer is she travels with him – and hides her trip from Mulder.