S6, E1: In the sixth season premiere, it's a year after Sam and Dean faced the Apocalypse. Dean has given up hunting and is living with Lisa (guest star CINDY SAMPSON) and her son Ben (guest star NICHOLAS ELIA). Mysteriously freed from his cage in hell, Sam finds Dean and tells him he needs to rejoin the fight and introduces Dean to a world - and a family - he never even knew existed: the Campbells, his mother's family, lead by none other than their Grandfather Samuel (guest star MITCH PILEGGI).