"Pablo" features a 5-year-old-boy on the autism spectrum who creates incredible imaginary friends who come to life through his magic crayons. Pablo and his friends go on adventures and they even help him with situations that may make him anxious such as going to the supermarket. The main cast of "Pablo" are all on the autism spectrum and some have even co-written some of the scripts. Every episode explores storylines that are honest and humorous and are inspired by real-life experiences of these children.