Pelakon & Kru
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Steve CarellYoung Gru - Sandra BullockScarlet Overkill
- Jon HammHerb Overkill
- Michael KeatonWalter Nelson
- Allison JanneyMadge Nelson
- Steve CooganProfessor Flux
- Jennifer SaundersThe Queen
- Pierre CoffinKevin the Minion/Bob the Minion/Stuart the Minion/Additional Minions
- Katy MixonTina
- Michael BeattieVNC Broadcaster/Highlight Reel Announcer/Walter Jr.
- Hiroyuki SanadaSumo Villain
- Geoffrey RushNarrator
- Pierre CoffinPengarah
- Kyle BaldaPengarah
- Christopher MeledandriPenerbit
- Janet HealyPenerbit
- Chris RenaudPenerbit
- Brian LynchPenulis