Pelakon & Kru
-
Tobey MaguirePeter Parker / Spider-Man - Kirsten DunstMary Jane Watson
- James FrancoHarry Osborn
- Alfred MolinaDoc Ock / Dr. Otto Octavius
- Rosemary HarrisMay Parker
- J.K. SimmonsJ. Jonah Jameson
- Donna MurphyRosie Octavius
- Peter McRobbieOsCorp Representative
- John LandisDoctor
- Joey DiazTrain Passenger
- Daniel Dae KimRaymond
- Parry ShenVoice Artist
- Sam RaimiPengarah
- Avi AradPenerbit
- Joseph M. CaraccioloPenerbit
- Laura ZiskinPenerbit
- Kevin FeigePenerbit
- Stan LeePenerbit
- Alvin SargentPenulis
- Alfred GoughPenulis
- Miles MillarPenulis
- Michael ChabonPenulis