Born in New Jersey but raised in Michigan, Grenier performed on the high school stage, but didn't start his screen career until his mid-thirties. Paying his dues with brief spots on episodes of crime shows such as "Miami Vice" (NBC, 1984-1990), he worked his way up to small movie roles, notably appearing in Oliver Stone's biting 1988 drama "Talk Radio" before winning parts in even bigger films such as the Johnny Depp/Al Pacino mob tale "Donnie Brasco." In 1999, Grenier was featured as Richard Chesler, the rigid and uncaring boss of Edward Norton's restless character in David Fincher's stylized and darkly comedic "Fight Club," and this turn increased his visibility, leading to various other film and TV roles. After being featured as the duplicitous Carl Webb in the first season of "24," he signed on as a regular on the lauded crime drama "Touching Evil" (USA Network, 2004), starring Jeffrey Donovan and Vera Farmiga, but the promising show was cancelled after a handful of episodes. Fortunately, Grenier was also appearing on the gritty Western series "Deadwood" at the time, portraying gambler Andy Cramed, who naturally finds trouble in the seedy and violent frontier town. In 2007, he reunited with Fincher for a small role in the ensemble murder mystery "Zodiac" and subsequently continued to juggle movie spots with guest shots on TV shows, making a habit of working on almost every procedural drama under the sun, including various incarnations of the "Law & Order" and "CSI" franchises. Having made infrequent appearances on Broadway over the years, Grenier garnered a Tony nomination for his role as Ludwig van Beethoven in the play "33 Variations," also featuring Jane Fonda. However, he soon returned to TV, taking on the recurring part of lawyer David Lee on the legal drama "The Good Wife." For the fifth season of the show in 2013, he was bumped up to a regular character, and that year Grenier also filmed his role as a politician in the sci-fi reboot movie "RoboCop" (2014).