After several of Bailey's patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
Castle is abducted and forced to solve deranged puzzles and mind games with strangers; Beckett and the 12th precinct race to save Castle.
After a woman discovers that her husband has been murdered, the investigation reveals that the victim may have been living a double life.
A notable county prosecutor is arrested for murder; when Angela hears that Maura is planning to meet Jack's daughter, she sets out to educate Maura about the interests of children today.
The squad is forced to work with a private investigator when a clothing designer is found poisoned and his wife reported missing; Jane asks Maura to teach her mother how to handle her finances.