Izzie's medical condition requires a difficult surgery; one of Owen's PTSD episodes causes Cristina to be injured.
Street's foster brother Nate is ensnared in a criminal enterprise that could ruin them both; a ruthless crew uses deadly force while stealing from card casinos; Buck approaches Deacon to partner on a private security opportunity.
Willis continues to tend to Rox's medical needs; Leanne and Max's father go searching for Ariel; Noa and Mario realize their career choices will mean ending their relationship.