Dr. Charles and Goodwin fear Dr. Halstead is repeating his past mistakes when a patient with early onset Alzheimer's is brought into the E.D.; Maggie and Ben are concerned when one of Ben's students is admitted; Dr. Manning and Dr. Marcel disagree.
Dr. Charles and Dr. Manning treat a patient who is fully invested in pretending to be someone other than himself; Noah doubts his abilities as a doctor; Dr. Marcel and Dr. Choi face a tough ethical decision; Dr. Halstead puts his faith in an addict.
Dr. Choi and Dr. Marcel don't see eye to eye over the treatment of a patient's chronic pain; rumors circulate about Maggie; Dr. Manning works to help a young boy, but she is challenged by his parents, who believe in only using holistic remedies.
Dr. Manning's actions with a recent patient lead to serious repercussions; April and Noah disagree over a patient who is injured after a beating; Dr. Charles is visited by a childhood friend.
Drs. Manning and Rhodes suspect that two separate cases involving sick babies may be connected; a homeless patient's upbeat disposition enlightens Drs. Halstead and Charles; Dr. Choi and a Navy corpsman deal with the toll of gang violence.
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