Regi Davis

All reassess their personal lives after witnessing a chance reunion between two long-lost lovers in the emergency room; Karev treats a troubled teen; Meredith shares her suspicions with Cristina.

Prentiss resigns, Hotch requests a transfer and Gideon goes missing, leaving the team three members short as they hunt a serial killer in Milwaukee, who kidnaps women from public places.

While undergoing aggressive cancer treatment, Izzie focuses on planning Meredith and Derek's wedding; Callie's father visits; Owen seeks help with his PTSD.

Michael is so smitten with Gob's girlfriend that he decides to let her know that Gob has been cheating on her, and Lucille tries to break up Buster and Lucille Austero.

A local nursing home provides an unlikely lead for Nick and Hank, while Eve visits Adalind for answers, and Renard confronts Nick.

While Michael is questioned by the police about Kitty's disappearance, Gob takes George-Michael shoplifting at the department store where Lindsey just got a job.