Cardia, a young woman who harbours a deadly poison in her body that harms all living things she touches, grows up confined in a mansion alone, feared by others as a monster.

Lupin and his companions use the mansion of a noble named Saint-Germain as their hideout; when Cardia meets Saint, he makes a comment that seems to carry a deeper, hidden meaning.

A thief has been making appearances all over London going after various treasures from vampire households.

Lupin and the rest plan to capture the train Finis is riding; Lupin and Cardia come up with a disguise.

Thanks to Finis, Lupin and the others are on the wanted list after the train explosion, making their search in London for information on Isaac difficult. Fran shuts himself up in his lab, making Cardia worry.

A mafia-sponsored airship race touts the posthumous writings of Isaac Beckford as the grand prize; Lupin and the others believe the writings might give them some clues about Isaac, so they enter the race.