Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.
Condemned man Howard Epps is scheduled to be executed by lethal injection in 32 hours for the murder of 17-year-old April Wright. Epps’ attorney, Amy Morton, makes a last-minute appeal to Booth, the man who arrested Epps, to re-examine the case. Booth believes Epps is guilty, but acknowledges that the case had a few loose ends.
Frasier attempts to work his psychoanalyses on a self-confessed lazy criminal, Phil, who has stolen his briefcase and his car. To make matters worse, Phil is masquerading as the `real' Frasier Crane.
Addison and Charlotte fight to save the lives of a woman in a coma and her unborn child; members of the Oceanside staff clash with Meg; when a patient is suspected of murdering his wife, Violet seeks Kevin's advice.
Malcolm enjoys baby-sitting for a normal family until he realises that he has been under camera surveillance.
