Patrick Cavanaugh

A gas tanker explodes on a highway, resulting in multiple injuries; Jo and Meredith try to help a frantic woman, whose child has a mysterious illness; Alex is forced to work with Jo's boyfriend.

When Patrick Jane once again takes on cult leader Bret Stiles (Malcolm McDowell), Stiles offers Jane information regarding Red John and the missing psychic, Kristina Frye (Leslie Hope).

When a missile test is hijacked and sent off course, the team searches for the hacking group responsible for the attack with the help of a computer specialist Hetty brings in to assist the team.

As Daisy and Simmons struggle to discover an escape route to the real world, the identity of the Inhuman leader of the resistance is revealed.

The truth behind Fitz's turn threatens to bring down all of S.H.I.E.L.D.

Daisy and Simmons race against the clock to get the team out of the Framework, but not everyone is ready to leave.