Pej Vahdat

In the series premiere, we meet the fabulously dysfunctional Gallagher family of working-class Chicago. Dad's a drunk; Mom split long ago; eldest daughter Fiona tries to hold the family together; eldest son Philip (Lip) tutors the neighborhood girls in physics and is repaid in kind; middle son Ian is grappling with homosexuality -- and being grappled by his married Pakistani employer at the corner liquor store; youngest daughter Debbie is stealing money from her UNICEF collection to help put food on the table; ten year old Carl is a budding sociopath and arsonist; and toddler Liam is -- well, he might actually be black, but nobody has a clue how. Meanwhile, the electric bill is due, there's no money, and someone has to look after the baby... It's one day at a time for this crazy dysfunctional family, but their mutual love and support for each other always see them through.

Richard tries to get Adele into Derek and Meredith's Alzheimer's trial; Arizona and Mark try to plan a baby shower for Callie; Henry has another medical complication; competition for the chief resident position is amplified.

When a letter from Carl's teacher arrives at the Gallagher home, Fiona is thrown into action to prove it's a suitable domicile for rehabilitating a delinquent. Lip has been contributing to the family bank account with proceeds from test-taking for his fellow students. His reputation for excelling at the SAT is getting around, and word spreads to some people he would rather have kept unaware. The Kash and Grab continues to get pilfered by a local hood, and Kash (guest star PEJ VAHDAT) and Ian are both ashamed at their inability to stop it. Meanwhile, Frank's bad business sense continues to yield consequences he's unprepared to embrace.

Fiona enjoys her youth by bartending and hanging out with a young exec; Debbie runs a daycare.

Everyone is a suspect when a body is found murdered at a popular nightclub known as “The Lab.” In an unusual twist of storytelling, Brennan, Booth and the Jeffersonian team take on various roles outside their normal duties, including serving as the nightclub staff as well as local law enforcement. A slew of special guest stars, including Max Keenan (guest star O’Neal), Jared Booth (guest star Fehr) and the members of Mötley Crüe, pay a visit.