Elaine Kao

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part One of a two-part episode.

Ted is stunned to learn that Stella expects him to move to New Jersey after they wed.

Larry offends a Japanese restaurant owner and accuses his dad's retirement home of fixing their bingo game.

David and Keith become comfortable with family life; Ruth finds empowerment; Brenda faces several truths; Nate brings the family together.

The team investigates the death of a lieutenant, which appears to be suicide; Nate joins Kensi in the field.