Michael Nathanson

Dr Charles faces a difficult case involving a patient who wants to remove his own arm, while Halstead and Goodwin try to help a grieving widower.

Thackery eschews Zinberg's advice at Mt. Sinai and opts for a dramatic, and risky, alternative course of action. Cornelia confronts Henry about his role in the business. Barrow defends his actions at the hospital construction site. Cleary refuses to give up on Harriet.

President Dalton's mental status is questioned when he threatens Russia over their potential role in a sonic attack at the U.S. embassy in Bulgaria.

A subway explosion leads to an influx of patients at The Knick, but little margin for profit. Pursued by Henry, Lucy takes to heart advice from one of Ping Wu's girls. An addict's misfortune gives Thackery an ideal test case for his latest theory on addiction.