Sydney Bristow is a grad student by day, international spy by night. Her happiness over new new engagement is short-lived as she learns some truths about who she works for.

Sydney finds trouble in the form of her arch nemesis while in Madrid to retrieve a 500-year-old sketch, and Will investigates Danny's death.

Sydney and Dixon take on a case involving the safety of the United Commerce Organization, and Francie confronts her boyfriend about his secret meetings with a woman.

Will tells Francie that he's been investigating the death of Danny. Sydney learns from Vaughn that her father may also be working for the FBI.

Sydney goes under cover in a mental institution to obtain information from an assassin who has been programmed to forget his deadly profession.