Exploring the epicentre of America's struggle with opioid addiction, from the boardrooms of Purdue Pharma, to a distressed Virginia mining community and to the hallways of the DEA.
EPISODE 1
First Bottle
Richard Sackler launches a powerful new painkiller and a rural doctor is introduced to the drug. Also, a coal miner plans her future, a DEA Agent learns of black market pills, and federal prosecutors decide to open a case into OxyContin.
EPISODE 2
Breakthrough Pain
OxyContin is on the market but faces a potential threat, Purdue's vast influence reaches the town of Finch Creek, Bridget steps outside her DEA authority, and the criminal investigation of OxyContin begins.
EPISODE 3
The 5th Vital Sign
Doctor Finnix begins to taper Betsy off OxyContin; Bridget sees the toll the drug is taking on communities; Rick and Randy investigate the world of pain societies; as sales climb, Richard Sackler makes bigger plans for his new drug.
EPISODE 4
Pseudo-Addiction
Sky-high OxyContin sales are threatened by reports of abuse, prosecutors investigate a claim central to OxyContin marketing, and Finnix begins to question the safety of the drug.
EPISODE 5
The Whistleblower
With OxyContin abuse spreading across the country, Bridget brings the fight to Purdue. Also, Rick and Randy seek to find a whistle-blower within Purdue to tie their case together.
EPISODE 6
Hammer the Abusers
Richard Sackler faces a catastrophic challenge to Purdue's bottom line, Bridget takes her fight to the FDA, Finnix reassesses his life as Betsy struggles to kick her addiction, and Rick and Randy find a bombshell piece of evidence.
Michael Keaton
Rosario Dawson
Peter Sarsgaard
Kaitlyn Dever
Will Poulter
John Hoogenakker
Michael Stuhlbarg
Mare Winningham
Beth Macy
Warren Littlefield
Danny Strong
