Christopher Duntsch begins operating at a Dallas hospital where he leaves two patients seriously maimed and another dead. Dr Henderson and Dr Kirby investigate whether Duntsch's surgical abilities amount to incompetence or murder.

Henderson and Kirby discover a history of Duntsch's medical misadventures and set out to strip him of his medical license. Duntsch obsessively struggles to make the football team at Colorado State before moving home and pursuing a career in medicine.

Duntsch studies under a renowned neurosurgeon while seeking a patent for his stem cell research. Henderson and Kirby discover a series of disturbing revelations about the medical system's accountability.

Henderson and Kirby confront a systemic failure. In a flashback, Duntsch sets up his private practice in Texas and is recruited by one of the nation's premier hospitals.

Assistant District Attorney Michelle Shughart joins Henderson and Kirby in exploring legal solutions while Duntsch is recruited by a prestigious medical centre.

After a devastating week in the O.R., Duntsch has his privileges suspended pending a drug test.