Seventeen-year-old Colombian Maria (Catalina Sandino Moreno) is desperate: pregnant and with a large family to care for, she's forced to leave a demanding job after an altercation with her boss. Needing work as soon as possible, she encounters charming Franklin (John Álex Toro), who offers her a dangerous job as a drug mule. With cocaine pellets in her stomach, Maria flies to New York for the drug drop-off, but finds her new line of work may be far riskier than it initially seemed.