Regi Davis

The team pursues a serial killer in Milwaukee, with three fewer members since Hotch asked to be transferred, Prentiss quit, and Gideon is missing.

While undergoing aggressive cancer treatment, Izzie focuses on planning Meredith and Derek's wedding; Callie's father visits; Owen seeks help with his PTSD.

All reassess their personal lives after witnessing a chance reunion between two long-lost lovers in the emergency room; Karev treats a troubled teen (Demi Lovato); Meredith shares her suspicions with Cristina.

Michael's medical condition forces him to go to the hospital; Lincoln and Sucre get into an explosive situation; Agent Self meets with a shocking ally.

Michael is so smitten with Gob's girlfriend that he decides to let her know that Gob has been cheating on her, and Lucille tries to break up Buster and Lucille Austero.

After a series of brutal and deadly attacks, Nick & Hank find an unlikely lead in a local nursing home; Eve goes to Adalind to get answers.