Meredith and Dr. Shepherd have to use more than medicine when a young woman's traditionalist, religious father forbids her to have a life-saving operation.
Five-0 tries to protect a wounded Gabriel and plan an escape when enemy gunmen storm the dilapidated building in which Gabriel is trapped.
As Celia deals with the other woman in her marriage Nancy contemplates creating a cover business to solve the cash-only financial issues caused by her drug dealing. Silas has to deal with his girlfriend's sudden departure when her mother sends her to Mexico while Shane tries to come to terms with missing his Dad.
Drs. Carter and Chen treat a frightened nanny who may have been impregnated by her employer; doctors frown on a new resident's (Don Cheadle) bedside manner.
As the threat escalates with the return of translucent shapeshifters, a former Massive Dynamic scientist gets involved; Nina Sharp visits Walter in the lab.
