"Scrubs" focuses on the bizarre experiences of fresh-faced medical intern John "J.D." Dorian (Zach Braff, "The Broken Hearts Club") as he embarks on his career in a surreal hospital crammed full of unpredictable staffers and patients - where humor and tragedy can merge paths at any turn. Joining the rumpled J.D. on his first day are his college buddy, Chris Turk (Donald Faison, "Remember the Titans"), an intern with a more elite surgical group, and J.D.'s fellow medical intern, the beautiful and driven Elliot Reid (Sarah Chalke, "Roseanne"). Meanwhile, the sobering reality of patients' needs has J.D.'s head spinning and his confidence is challenged by the fatherly chief of medicine, Dr. Bob Kelso (Ken Jenkins, "Courage Under Fire"). However, with the help of the abrasive, worldly Dr. Perry Cox (John C. McGinley, "Wall Street") and caring nurse Carla Espinosa (Judy Reyes, "Oz"), the neophyte doctor works through his mistakes and discovers that he is up to the job in this brave new world.

J.D. (Zach Braff) shows genuine concern for a flaky patient (guest star John Ducey) after a cancer scare, but when the man continues to puff away daily on multiple packs of cigarettes, J.D. seeks advice from his gruff mentor Dr. Cox (John C. McGinley) on how to intervene -- and instead gets smacked as a professional courtesy. Elsewhere, Elliot's (Sarah Chalke) unsociable bedside manner and attitude makes her public enemy number-one among the nurses -- especially Carla (Judy Reyes). Meanwhile, Carla's got her hands full as she rebuffs an eager Turk (Donald Faison) who persists in asking her out on a date. Ken Jenkins also stars.

When Turk (Donald Faison) always seems occupied with new girlfriend Carla (Judy Reyes) and with work, a resentful J.D. (Zach Braff) feels like an odd-man-out and abandoned by his buddy -- especially when he believes that Turk botched a patient's surgery that could also implicate him for not reporting the mistake. In addition, J.D. is even more distracted by his tempting flirtations with Elliot (Sarah Chalke) but he feels that unless he makes a more serious romantic maneuver within 48 hours, their budding relationship will be forever doomed and downgraded to merely "friends" status. Elsewhere, Elliot seeks advice from a resentful Dr. Cox (John C. McGinley) who hardly relishes becoming the interns' designated mentor. Ken Jenkins also stars.

J.D. (Zach Braff) remembers the medical fact that almost one of three patients dies in the hospital when he forms a bond with a sweet elderly patient (guest star Kathryn Joosten, NBC's "The West Wing") whose kidneys are failing. But when she refuses to undergo dialysis, she must prepare herself -- and a disconsolate J.D. -- for the inevitable. At the same time, Elliot (Sarah Chalke) duels with a hissing Carla (Judy Reyes) as she tries to treat a Hispanic-speaking woman and Turk (Donald Faison) is shocked when he performs surgery on a likable hernia patient (guest star Travis Webster). John C. McGinley and Ken Jenkins also star.

J.D.(Zach Braff) is torn when he discovers that Dr. Cox (John C. McGinley) has falsely appropriated the medical insurance of a deceased patient in order to help another more needy patient but when he inadvertently informs Cox' rival -- the nasty Dr. Kelso (Ken Jenkins) -- the two veteran doctors battle for J.D.'s soul during a good-vs.-evil game of golf. Meanwhile, Turk (Donald Faison) frets that his girlfriend Carla (Judy Reyes) might figure out where he got his new gift for her. Sarah Chalke also stars. Louie Anderson ("Family Feud") guest-stars as himself.

An overwhelmed J.D. (Zach Braff) is assigned to treat a demanding and demeaning patient (guest star Christa Miller, "The Drew Carey Show") who is an important hospital board member while he is distracted by the bad news that his gruff mentor, Dr. Cox (John C. McGinley), could be summarily fired by the nasty Dr. Kelso (Ken Jenkins). Elsewhere, a frustrated Turk (Donald Faison) tries to negotiate his romance with Carla (Judy Reyes) around the looming presence of her intrusive Hispanic mother (guest star Gina Morelli) while Elliot (Sarah Chalke) seeks professional help from her patient -- a psychiatrist whose jaw has been wired shut. Jimmie "J.J." Walker ("Good Times") also guest-stars as himself.